The Jackson Laboratory

Center for Biometric Analysis

What We Do

At the Center for Biometric Analysis (CBA), we empower JAX scientists with cutting-edge in vivo mouse phenotyping services. Our expertise spans a wide range of biological domains and disease states. Beyond data acquisition, we offer comprehensive support through experimental design consultation, staff training, and rigorous data quality control, statistical analysis, and interpretation.

Services and Technologies Offered

The CBA offers comprehensive in vivo mouse phenotyping services through four specialized cores:

  • Neurobehavioral Phenotyping (NBP core)
  • Physiology and Cardiac Phenotyping (PCP core)
  • Metabolic Phenotyping (MEP core)
  • Pre-clinical Imaging (PCI core)

Each core provides a range of services tailored to specific research needs. As our equipment and technologies evolve, the services we offer may also change to ensure we continue to meet the highest standards of scientific research.

Assays by Service Core

NBP Adhesive Tape RemovalPCP Fundus Imaging/Florescence Angiography
NBP Circadian Activity Monitoring (Wheels)PCP Gross Morphology Photography
NBP Elevated Zero MazePCP Intraocular Pressure Measurement, Non-Invasive
NBP Delayed Spatial Alternation (Y-Maze)PCP Optical Coherence Tomography
NBP Fear Conditioning, Contextual and CuedPCP Piezoelectric Sleep Monitoring
NBP Frailty ScreenPCP Slit Lamp Ophthalmoscopy
NBP Gait Analysis (Treadscan)PCP Visual Acuity
NBP Grip StrengthPCP Visual Evoked Potential
NBP Grooming, Induced and SpontaneousMEP Body Composition Analysis-EchoMRI
NBP Home Cage Monitoring (Phenotypers)MEP Indirect Calorimetry
NBP Home Cage Wheel Running (Wheels)MEP Insulin Tolerance Test
NBP Hot PlateMEP Glucose Tolerance Test-Intraperitoneal
NBP Light/Dark BoxMEP Glucose Tolerance Test-Oral
NBP Nest BuildingMEP Glucose Tolerance Test with Insulin-Oral
NBP Novel Object RecognitionMEP Hyperglycemic Clamps (Glucose Clamps)
NBP Open FieldMEP Mixed Meal Tolerance Test
NBP Passive AvoidanceMEP Mixed Meal Tolerance Test with C-peptide
NBP Place Object RecognitionMEP Subcutaneous Temperature Monitoring
NBP Pre-pulse Inhibition/Startle ReflexMEP Treadmill Activity
NBP RotarodPCI MRI-Anatomical
NBP Social Approach (3-Chamber)PCI MRI-Angiography
NBP Spontaneous Alternation-Visual Cues (Y-Maze)PCI MRI-Diffusion Tensor Imaging
NBP Stress Induced HypethermiaPCI MRI-Diffusion Weighted Imaging, Isotropic
NBP Tail SyspensionPCI MRI-Neurite Orientation Dispersion and Density Imaging
NBP Von FreyPCI MRI-Neuroanatomical
PCP Auditory Brainstem ResponsePCI MRI-Neuroanatomical, Isotropic
PCP Blood Pressure, Non-InvasivePCI MRI-Resting State Functional (rsfMRI)
PCP Direct & Indirect Ophthalmic Exam and Ocular ImagingPCI MRI-rsfMRI, Isotropic (imaging acquisition only)
PCP Distortion Product Otoacoustic EmissionPCI MRI Susceptibility Weighted Imaging
PCP DSI Telemetry Cardiovascular Blood PressurePCI MRI-T2star Mapping, Isotropic
PCP DSI Telemetry EEG/EMG-Deep Brain EEGPCI uCT-in vivo Imaging
PCP DSI Telemetry EEG/EMG-SeizuresPCI uCT-ex vivo Imaging (Trabecular and Cortical Bone Quantification)
PCP DSI Telemetry EEG/EMG-SleepPCI 2D Digital X-ray Skeletal Imaging
PCP EchocardiographyPCI Dual-Emission X-ray Absorptiometry
PCP Electrocardiogram, AnesthetizedPCI Ultrasonography
PCP Electroretinography 

 

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